Heidi Rosenburg, Ph.D. - Academic Achievements

PhD in Medicinal Chemistry. University of Bath. UK 2002

Thesis: Synthesis and Biological Activity of mimics of D-myo-inositol 1,4,5-trisphosphate and adenophostin A.

Bachelor of Science. Chemistry. University of Liverpool. UK 1997

Honors project. Synthesis of nitrones. Grade-First class with honors. Majoring in organic chemistry.

Publications

Pettit, G. R., Rosenberg, H. J., Dixon, R., Knight, J.C., Hamel, E., Chapuis, J-C., Pettit, R. K., Hogan, F., Sumner, B., Ain, K. B and Trickey-Platt, B. “Antineoplastic agents. 548. Synthesis of iodo- and diiodocombstatin phosphate prodrugs.” J. Nat. Prod., 2012, 75 (3), pp 385–393

Pettit, G. R., Minardi, M. D., Rosenberg, H. J., Hamel, E., Bibby, M. C., Martin, S. W., Jung, M. K., Pettit, R. K., Cuthbertson, T. J. and Chapuis, J-C. “Antineoplastic agents 509: Synthesis of fluorocombstatin phosphate and related 3-halostilbenes.” J. Nat. Prod., 2005, 68 (10), pp 1450-8.

Rosenberg, H. J., Riley, A. M., Laude, A. J., Taylor, C. W. and Potter, B. V. L. “Synthesis and Ca -mobilizing activity of purine-modified mimics of adenophostin A: A model for the adenophostin-Ins(1,4,5)P receptor interaction.” J. Med. Chem, 2003, 46 (23), pp 4860-71.

Wagner, G. K., Riley, A. M., Rosenberg, H. J., Taylor, C. W., Andreas G. H. and. “Analogues. Supplement (2001) 2003, (3), pp 1-2. Nucleic acids research. of cyclic adenosine 5'-diphosphate ribose and adenophostin A, nucleotides in cellular signal transduction.” Potter, B. V. L.

Rosenberg, H. J., Riley, A. M, Marwood, R.D., Correa, V., Taylor, C. W. and Potter, B. V. L. “Xylopyranoside-based agonists of D-myo-inositol 1,4,5-trisphosphate receptors: synthesis and effect of stereochemistry on biological activity.” Carbohydr. Res., 2001, 332, 53-66.

Rosenberg, H. J., Riley, A. M., Correa, V., Taylor, C. W. and Potter, B. V. L. “C-Glycoside based mimics of D-myo-inositol 1,4,5-trisphosphate.” Carbohydr. Res., 2000, 329, 7-16.

Patents and intellectual property

US Patent 7223747 and US Patent 7507851 - Halocombstatins and methods of synthesis thereof. Inventors: Pettit, G. R., Rosenberg, H. J., and Minardi, M. D.

AzTE case # M03-068 and M05-030. Halocombstatins. Inventors: Pettit, G. R., Rosenberg, H. J., and Minardi, M. D.

Awards and Honors

RSC Carbohydrate Bursary 2002

Wellcome Trust Prize Fellowship 1998-2002

Presentations

XXI International Carbohydrate Symposium in Cairns. 2002. Poster presentation.

RSC University of Warwick. 2002. Oral presentation

RSC Carbohydrate Group Meeting, Dublin, April 2001. Poster presentation.

RSC International Symposium: Synthesis in Organic Chemistry. University of Manchester. 2001 Poster presentation